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Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10285730" target="_blank" >RIV/00216208:11110/15:10285730 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1111/dgd.12193" target="_blank" >http://dx.doi.org/10.1111/dgd.12193</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/dgd.12193" target="_blank" >10.1111/dgd.12193</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development

  • Original language description

    A central function of the Drosophila salivary glands (SGs), historically known for their polytene chromosomes, is to produce and then release during pupariation the secretory glue used to affix a newly formed puparium to a substrate. This essential eventin the life history of Drosophila is regulated by the steroid hormone ecdysone in the late-larval period. Ecdysone triggers a cascade of sequential gene activation that leads to glue secretion and initiates the developmentally-regulated programmed celldeath (PCD) of the larval salivary glands, which culminates 16 h after puparium formation (APF). We demonstrate here that, even after the larval salivary glands have completed what is perceived to be one of their major biological functions - glue secretion during pupariation - they remain dynamic and physiologically active up until the execution phase of PCD. We have used specific metabolic inhibitors and genetic tools, including mutations or transgenes for shi, Rab5, Rab11, vha55, vha68

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Development Growth and Differentiation

  • ISSN

    0012-1592

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    JP - JAPAN

  • Number of pages

    23

  • Pages from-to

    74-96

  • UT code for WoS article

    000348711000007

  • EID of the result in the Scopus database

    2-s2.0-84929143772