Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10285730" target="_blank" >RIV/00216208:11110/15:10285730 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/dgd.12193" target="_blank" >http://dx.doi.org/10.1111/dgd.12193</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/dgd.12193" target="_blank" >10.1111/dgd.12193</a>
Alternative languages
Result language
angličtina
Original language name
Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development
Original language description
A central function of the Drosophila salivary glands (SGs), historically known for their polytene chromosomes, is to produce and then release during pupariation the secretory glue used to affix a newly formed puparium to a substrate. This essential eventin the life history of Drosophila is regulated by the steroid hormone ecdysone in the late-larval period. Ecdysone triggers a cascade of sequential gene activation that leads to glue secretion and initiates the developmentally-regulated programmed celldeath (PCD) of the larval salivary glands, which culminates 16 h after puparium formation (APF). We demonstrate here that, even after the larval salivary glands have completed what is perceived to be one of their major biological functions - glue secretion during pupariation - they remain dynamic and physiologically active up until the execution phase of PCD. We have used specific metabolic inhibitors and genetic tools, including mutations or transgenes for shi, Rab5, Rab11, vha55, vha68
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Development Growth and Differentiation
ISSN
0012-1592
e-ISSN
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Volume of the periodical
57
Issue of the periodical within the volume
1
Country of publishing house
JP - JAPAN
Number of pages
23
Pages from-to
74-96
UT code for WoS article
000348711000007
EID of the result in the Scopus database
2-s2.0-84929143772