Chronic stress-like syndrome as a consequence of medial site subthalamic stimulation in Parkinson's disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294720" target="_blank" >RIV/00216208:11110/15:10294720 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/15:10294720

Result on the web

<a href="http://dx.doi.org/10.1016/j.psyneuen.2014.12.001" target="_blank" >http://dx.doi.org/10.1016/j.psyneuen.2014.12.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.psyneuen.2014.12.001" target="_blank" >10.1016/j.psyneuen.2014.12.001</a>

Result language

angličtina

Original language name

Chronic stress-like syndrome as a consequence of medial site subthalamic stimulation in Parkinson's disease

Original language description

Considering the functional organization of the subthalamic nucleus (STN), we hypothesized that subthalamic deep brain stimulation (STN-DBS) in Parkinson's disease might have a differential impact on the hypothalamic-pituitary-adrenal axis in relation tothe position of active stimulating contact within the STN. In addition, we searched for any STN-DBS-related morning plasma cortisol changes in association with postoperative anxiety and weight gain. A plasma cortisol measurement was performed on the dayof initiation of bilateral STN-DBS and repeated after 1 and 17 months in twenty patients with advanced Parkinson's disease. The body weight change and anxiety scores following the implantation were assessed as well. The electrode positions in the STN were determined on T1-weighted magnetic resonance images. After initiation of stimulation, cortisol levels significantly decreased and the cortisol changes after 1 and 17 months strongly correlated with the position of active contact in the

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Psychoneuroendocrinology

ISSN

0306-4530

e-ISSN

—

Volume of the periodical

52

Issue of the periodical within the volume

February

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

302-310

UT code for WoS article

000349271000029

EID of the result in the Scopus database

2-s2.0-84922649660