Prevalence, severity and correlates of fatigue in newly diagnosed patients with myelodysplastic syndromes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294763" target="_blank" >RIV/00216208:11110/15:10294763 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/15:10294763
Result on the web
<a href="http://dx.doi.org/10.1111/bjh.13138" target="_blank" >http://dx.doi.org/10.1111/bjh.13138</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/bjh.13138" target="_blank" >10.1111/bjh.13138</a>
Alternative languages
Result language
angličtina
Original language name
Prevalence, severity and correlates of fatigue in newly diagnosed patients with myelodysplastic syndromes
Original language description
The primary objective of this study was to investigate factors associated with fatigue severity in newly diagnosed patients with higher-risk myelodysplastic syndromes (MDS). The secondary objectives were to assess symptom prevalence and to examine the relationships between fatigue, quality of life (QoL) and overall symptom burden in these patients. The analyses were conducted in 280 higher-risk MDS patients. Pre-treatment patient-reported fatigue was evaluated with the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue scale and QoL was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). Female gender (P=0018), poor performance status (i.e., ECOG of 2-4) (P<0001) and lower levels of haemoglobin (Hb) (P=0026) were independently associated with higher fatigue severity. The three most prevalent symptoms were as follows: fatigue (92%), dyspnoea (63%) and pain (55%). Patients with higher levels of
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
British Journal of Haematology
ISSN
0007-1048
e-ISSN
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Volume of the periodical
168
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
361-370
UT code for WoS article
000348845500007
EID of the result in the Scopus database
2-s2.0-84921434407