Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294834" target="_blank" >RIV/00216208:11110/15:10294834 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/ije/dyu255" target="_blank" >http://dx.doi.org/10.1093/ije/dyu255</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/ije/dyu255" target="_blank" >10.1093/ije/dyu255</a>

Result language
angličtina
Original language name
Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium
Original language description
Background: Increasing incidence of head and neck cancer (HNC) in young adults has been reported. We aimed to compare the role of major risk factors and family history of cancer in HNC in young adults and older patients. Methods: We pooled data from 25 case-control studies and conducted separate analyses for adults <= 45 years old ('young adults', 2010 cases and 4042 controls) and > 45 years old ('older adults', 17 700 cases and 22 704 controls). Using logistic regression with studies treated as randomeffects, we estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Results: The young group of cases had a higher proportion of oral tongue cancer (16.0% in women; 11.0% in men) and unspecified oral cavity / oropharynx cancer (16.2%; 11.1%) and a lower proportion of larynx cancer (12.1%; 16.6%) than older adult cases. The proportions of never smokers or never drinkers among female cases were higher than among male cases in both age groups. Positive associations with HNC
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)