Positive Influence of Being Overweight/Obese on Long Term Survival in Patients Hospitalised Due to Acute Heart Failure

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294889" target="_blank" >RIV/00216208:11110/15:10294889 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/15:00062870 RIV/00216224:14110/15:00085555 RIV/00216208:11120/15:43909615 RIV/65269705:_____/15:00062870 and 4 more
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0117142" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0117142</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0117142" target="_blank" >10.1371/journal.pone.0117142</a>

Result language
angličtina
Original language name
Positive Influence of Being Overweight/Obese on Long Term Survival in Patients Hospitalised Due to Acute Heart Failure
Original language description
Background Obesity is clearly associated with increased morbidity and mortality rates. However, in patients with acute heart failure (AHF), an increased BMI could represent a protective marker. Studies evaluating the "obesity paradox" on a large cohort with long-term follow-up are lacking. Methods Using the AHEAD database (a Czech multi-centre database of patients hospitalised due to AHF), 5057 patients were evaluated; patients with a BMI <18.5 kg/m(2) were excluded. All cause mortality was compared between groups with a BMI of 18.5-25 kg/m(2) and with BMI >25 kg/m(2). Data were adjusted by a propensity score for 11 parameters. Results In the balanced groups, the difference in 30-day mortality was not significant. The long-term mortality of patients with normal weight was higher than for those who were overweight/obese (HR, 1.36; 95% CI, 1.26-1.48; p<0.001)). In the balanced dataset, the pattern was similar (1.22; 1.09-1.39; p<0.001). A similar result was found in the balanced dataset
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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