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Comparing morbidity and cancer control after 3D-conformal (70/74 Gy) and intensity modulated radiotherapy (78/82 Gy) for prostate cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10295029" target="_blank" >RIV/00216208:11110/15:10295029 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/15:43909645 RIV/00216275:25520/15:39900944 RIV/00179906:_____/15:10295029

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s00066-014-0806-y" target="_blank" >http://dx.doi.org/10.1007/s00066-014-0806-y</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00066-014-0806-y" target="_blank" >10.1007/s00066-014-0806-y</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Comparing morbidity and cancer control after 3D-conformal (70/74 Gy) and intensity modulated radiotherapy (78/82 Gy) for prostate cancer

  • Original language description

    Purpose The purpose of this work was to compare toxicity and cancer control between patients with prostate cancer treated using three-dimensional conformal radiotherapy (3D-CRT) and those treated using intensity-modulated radiation therapy (IMRT). Methods and materials A total of 553 patients with prostate cancer were treated with 3D-CRT 70-74 Gy (3D-CRT 70, 3D-CRT 74) or IMRT 78-82 Gy (IMRT 78, IMRT/SIB 82). Late toxicity was scored according to FC-RTOG/LENT criteria. Biochemical failure was defined using the Phoenix and ASTRO definitions. Results The 5-year risk of grade 2-4 genitourinary toxicity was 26.3 % (3D-CRT 70), 27.2 % (3D-CRT 74), 17.3 % (IMRT 78), and 25.1 % (IMRT/SIB 82) without statistical differences. The 5-year risk of grade 2-4 gastrointestinal toxicity was 19.4 % (3D-CRT 70), 42.1 % (3D-CRT 74), 20.5 % (IMRT 78), and 26.6 % (IMRT/SIB 82). The differences between 3D-CRT 74 and 3D-CRT 70 and between 3D-CRT 74 and IMRT 78 were statistically significant (log rank p = 0.0

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Strahlentherapie und Onkologie

  • ISSN

    0179-7158

  • e-ISSN

  • Volume of the periodical

    191

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    9

  • Pages from-to

    338-346

  • UT code for WoS article

    000353219300006

  • EID of the result in the Scopus database

    2-s2.0-84933525368