Risk Factors for Neurodegeneration in Idiopathic Rapid Eye Movement Sleep Behavior Disorder: A Multicenter Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10295087" target="_blank" >RIV/00216208:11110/15:10295087 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/15:10295087

Result on the web

<a href="http://dx.doi.org/10.1002/ana.24385" target="_blank" >http://dx.doi.org/10.1002/ana.24385</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ana.24385" target="_blank" >10.1002/ana.24385</a>

Result language

angličtina

Original language name

Risk Factors for Neurodegeneration in Idiopathic Rapid Eye Movement Sleep Behavior Disorder: A Multicenter Study

Original language description

ObjectiveTo assess whether risk factors for Parkinson disease and dementia with Lewy bodies increase rate of defined neurodegenerative disease in idiopathic rapid eye movement (REM) sleep behavior disorder (RBD). MethodsTwelve centers administered a detailed questionnaire assessing risk factors for neurodegenerative synucleinopathy to patients with idiopathic RBD. Variables included demographics, lifestyle factors, pesticide exposures, occupation, comorbid conditions, medication use, family history, andautonomic/motor symptoms. After 4 years of follow-up, patients were assessed for dementia or parkinsonism. Disease risk was assessed with Kaplan-Meier analysis, and epidemiologic variables were compared between convertors and those still idiopathic using logistic regression. ResultsOf 305 patients, follow-up information was available for 279, of whom 93 (33.3%) developed defined neurodegenerative disease. Disease risk was 25% at 3 years and 41% after 5 years. Patients who converted were

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Neurology

ISSN

0364-5134

e-ISSN

—

Volume of the periodical

77

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

830-839

UT code for WoS article

000353235400011

EID of the result in the Scopus database

2-s2.0-84928215818