Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10295098" target="_blank" >RIV/00216208:11110/15:10295098 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/15:10295098
Result on the web
<a href="http://www.clinsci.org/content/129/1/1" target="_blank" >http://www.clinsci.org/content/129/1/1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1042/CS20140566" target="_blank" >10.1042/CS20140566</a>

Result language
angličtina
Original language name
Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases
Original language description
Bilirubin, the principal tetrapyrrole, bile pigment and catabolite of haem, is an emerging biomarker of disease resistance, which may be related to several recently documented biological functions. Initially believed to be toxic in infants, the perception of bilirubin has undergone a transformation: it is now considered to be a molecule that may promote health in adults. Data from the last decade demonstrate that mildly elevated serum bilirubin levels are strongly associated with reduced prevalence of chronic diseases, particularly cardiovascular diseases (CVDs), as well as CVD-related mortality and risk factors. Recent data also link bilirubin to other chronic diseases, including cancer and Type 2 diabetes mellitus, and to all-cause mortality. Therefore, there is evidence to suggest that bilirubin is a biomarker for reduced chronic disease prevalence and a predictor of all-cause mortality, which is of important clinical significance. In the present review, detailed information on the
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
<a href="/en/project/LH11030" target="_blank" >LH11030: Experimental studies of potential antiproliferative effects of edible algae</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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