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Vitamin D Binding Protein Is Not Involved in Vitamin D Deficiency in Patients with Chronic Kidney Disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10295121" target="_blank" >RIV/00216208:11110/15:10295121 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/15:10295121 RIV/00064165:_____/15:10295121

  • Result on the web

    <a href="http://dx.doi.org/10.1155/2015/492365" target="_blank" >http://dx.doi.org/10.1155/2015/492365</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1155/2015/492365" target="_blank" >10.1155/2015/492365</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Vitamin D Binding Protein Is Not Involved in Vitamin D Deficiency in Patients with Chronic Kidney Disease

  • Original language description

    Objective. This study was designed to evaluate vitamin D status with separate determination of 25-OH D-2 and 25-OH D-3 and its relationship to vitamin D binding protein (VDBP) in patients with chronic kidney disease (CKD) and long-term haemodialysis patients (HD). Methods. 45 CKD patients, 103 HD patients, and 25 controls (C) were included. Plasma vitamin D concentrations were determined using chromatography and VDBP in serum and urine in CKD using enzyme immunoassay. Results. Plasma vitamin D levels were lower in CKD (30.16 +/- 16.74 ng/mL) and HD(18.85 +/- 15.85 ng/mL) versus C(48.72 +/- 18.35 ng/mL), P < 0.0001. 25-OH D-3 was the dominant form of vitamin D. Serum VDBP was higher in CKD (273.2 +/- 93.8 ug/mL) versus C (222 +/- 87.6 ug/mL) and HD (213.8 +/- 70.9 ug/mL), P = 0.0003. Vitamin D/VDBP ratio was the highest in C and the lowest in HD; however, there was no correlation between vitamin D and VDBP. Urinary concentration of VDBP in CKD (0.25 +/- 0.13 ug/mL) correlated with prote

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BioMed Research International

  • ISSN

    2314-6133

  • e-ISSN

  • Volume of the periodical

    Neuveden

  • Issue of the periodical within the volume

    January

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

    000354683500001

  • EID of the result in the Scopus database

    2-s2.0-84929631170