Comparability of patients with ANCA-associated vasculitis enrolled in clinical trials or in observational cohorts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10295615" target="_blank" >RIV/00216208:11110/15:10295615 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/15:10295615
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Comparability of patients with ANCA-associated vasculitis enrolled in clinical trials or in observational cohorts
Original language description
Objective. To analyse the differences between patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) entered into randomised clinical trials (RCTs) and those followed in large observational cohorts. Methods. The main characteristics and outcomes of patients with generalised and/or severe GPA or MPA with a fivefactor score >= 1 enrolled in the French Vasculitis Study Group (FVSG) or the US-Canadian-based Vasculitis Clinical Research Consortium cohorts were compared to those enrolled in one of 2 FVSG clinical RCTs (WEG91, WE-GENT) or 3 European Vasculitis Society clinical trials (CYCLOPS, CYCAZAREM, IMPROVE). Results. 657 patients (653% with GPA) in RCTs were compared to 437 in cohorts (90.6% with GPA). RCT patients were older at diagnosis than the cohort patients (56.6 +/- 13.9 vs. 46.8 +/- 17.3 years), had higher Birmingham vasculitis activity score (19.5 +/- 9.1 vs. 16.9 +/- 7.4), and more frequent kidney disease (84.0% vs. 54.9%) but fewer ear, nose, a
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
—
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical and Experimental Rheumatology
ISSN
0392-856X
e-ISSN
—
Volume of the periodical
33
Issue of the periodical within the volume
2
Country of publishing house
IT - ITALY
Number of pages
7
Pages from-to
"S77"-"S83"
UT code for WoS article
000356402900013
EID of the result in the Scopus database
—