Screening for alpha-synuclein immunoreactive neuronal inclusions in the hippocampus allows identification of atypical MSA (FTLD-synuclein)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10296041" target="_blank" >RIV/00216208:11110/15:10296041 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/15:43909984
Result on the web
<a href="http://dx.doi.org/10.1007/s00401-015-1455-7" target="_blank" >http://dx.doi.org/10.1007/s00401-015-1455-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00401-015-1455-7" target="_blank" >10.1007/s00401-015-1455-7</a>

Result language
angličtina
Original language name
Screening for alpha-synuclein immunoreactive neuronal inclusions in the hippocampus allows identification of atypical MSA (FTLD-synuclein)
Original language description
Atypical multiple system atrophy (aMSA) is a term recently introduced by Aoki et al. to describe cases that show hallmark neuropathological changes of glial cytoplasmic inclusions (Papp-Lantos bodies) characteristic of MSA, while clinically presenting with frontotemporal dementia (FTD) syndromes associated with frontotemporal lobar degeneration (FTLD) and severe limbic and cortical ?-synuclein neuronal pathology. The authors evaluated FTD syndrome cases and showed that the evaluation of ?-synuclein immunoreactive neuronal cytoplasmic inclusions (NCIs) in the hippocampus (dentate gyrus and CA1/Subiculum) seems to be of great importance. We aimed to determine if these morphological features in the hippocampus are reliable to identify similar cases in ourarchives.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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