Panel of Urinary Diagnostic Markers for Non-Invasive Detection of Primary and Recurrent Urothelial Urinary Bladder Carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10296539" target="_blank" >RIV/00216208:11110/15:10296539 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/15:10296539
Result on the web
<a href="http://dx.doi.org/10.1159/000368166" target="_blank" >http://dx.doi.org/10.1159/000368166</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000368166" target="_blank" >10.1159/000368166</a>
Alternative languages
Result language
angličtina
Original language name
Panel of Urinary Diagnostic Markers for Non-Invasive Detection of Primary and Recurrent Urothelial Urinary Bladder Carcinoma
Original language description
Objectives: To determine the combination of urinary protein markers for noninvasive detection of primary and recurrent urothelial bladder carcinomas. Methods: Urinary concentrations of 27 biomarkers (NSE, ATT, AFABP, Resistin, Midkine, Clusterin, Uromodulin, ZAG2, HSP27, HSP 60, NCAM1/CD56, Angiogenin, Calreticulin, Chromogranin A, CEACAM1, CXCL1, IL13Ra2, Progranulin, VEGFA, CarbAnhydIX, Annexin-V, TIM4, Galectin1, Cystatin B, Synuclein G, ApoA1 and ApoA2) were assessed by enzyme-linked immunosorbent assay or by electrochemiluminiscence immunoassay. Results:During the primary diagnostics, a group of 70 patients with primary occurrence of bladder cancer and 49 healthy control subjects were compared. For this clinical situation, the most accurate combination proved to be the combination of cytology with markers Midkine and Synuclein G (sensitivity 91.8%, specificity 97.5%). During the monitoring of patients with non-muscle invasive bladder cancer (NMIBC), a group of 44 patients with can
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/FR-TI3%2F666" target="_blank" >FR-TI3/666: Identification of novel biomarkers panels in selected malignancies</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Urologia Internationalis
ISSN
0042-1138
e-ISSN
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Volume of the periodical
95
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
9
Pages from-to
56-64
UT code for WoS article
000359177200009
EID of the result in the Scopus database
2-s2.0-84939653663