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Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10297918" target="_blank" >RIV/00216208:11110/15:10297918 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/15:10297918 RIV/61388955:_____/15:00467500

  • Result on the web

    <a href="http://dx.doi.org/10.3109/15563650.2015.1059946" target="_blank" >http://dx.doi.org/10.3109/15563650.2015.1059946</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3109/15563650.2015.1059946" target="_blank" >10.3109/15563650.2015.1059946</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak

  • Original language description

    Context. Mass or cluster methanol poisonings are frequently reported from around the world. The comparative effectiveness of ethanol and fomepizole as antidotes for methanol poisoning is unknown due to the difficulty of performing a randomized controlledtrial. Objective. During an outbreak of mass poisonings in the Czech Republic in 2012-2014, we compared the effects of antidotes on the frequency of health sequelae and mortality. Methods. The study was designed as a cross-sectional case series and quasi-case-control study. Patients with a diagnosis of methanol poisoning on admission to hospitals were identified for the study. Diagnosis was established when (i) a history of recent ingestion of illicit spirits was available and serum methanol was higherthan 6.2 mmol/L (20 mg/dL), or (ii) there was a history/clinical suspicion of methanol poisoning, and serum methanol was above the limit of detection with at least two of the following: pH < 7.3, serum bicarbonate. 20 mmol/L, and anion g

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Toxicology

  • ISSN

    1556-3650

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    797-806

  • UT code for WoS article

    000361070000002

  • EID of the result in the Scopus database

    2-s2.0-84939599573