Early Inhaled Budesonide for the Prevention of Bronchopulmonary Dysplasia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10312640" target="_blank" >RIV/00216208:11110/15:10312640 - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/15:E0105213 RIV/00064165:_____/15:10312640
Result on the web
<a href="http://dx.doi.org/10.1056/NEJMoa1501917" target="_blank" >http://dx.doi.org/10.1056/NEJMoa1501917</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1056/NEJMoa1501917" target="_blank" >10.1056/NEJMoa1501917</a>
Alternative languages
Result language
angličtina
Original language name
Early Inhaled Budesonide for the Prevention of Bronchopulmonary Dysplasia
Original language description
BACKGROUND Systemic glucocorticoids reduce the incidence of bronchopulmonary dysplasia among extremely preterm infants, but they may compromise brain development. The effects of inhaled glucocorticoids on outcomes in these infants are unclear. METHODS Werandomly assigned 863 infants (gestational age, 23 weeks 0 days to 27 weeks 6 days) to early (within 24 hours after birth) inhaled budesonide or placebo until they no longer required oxygen and positive-pressure support or until they reached a postmenstrual age of 32 weeks 0 days. The primary outcome was death or bronchopulmonary dysplasia, confirmed by means of standardized oxygen-saturation monitoring, at a postmenstrual age of 36 weeks. RESULTS A total of 175 of 437 infants assigned to budesonide for whom adequate data were available (40.0%), as compared with 194 of 419 infants assigned to placebo for whom adequate data were available (46.3%), died or had bronchopulmonary dysplasia (relative risk, stratified according to gestational
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
<a href="/en/project/7E09060" target="_blank" >7E09060: Efficacy and Safety of Inhaled Budesonide in Very Preterm Infants at Risk for Bronchopulmonary Dysplasia</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
New England Journal of Medicine
ISSN
0028-4793
e-ISSN
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Volume of the periodical
373
Issue of the periodical within the volume
16
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
1497-1506
UT code for WoS article
000362880300006
EID of the result in the Scopus database
2-s2.0-84944463128