The Role of Steroid Hormones in the Development of Intrahepatic Cholestasis of Pregnancy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10313577" target="_blank" >RIV/00216208:11110/15:10313577 - isvavai.cz</a>
Alternative codes found
RIV/00023761:_____/15:#0000566 RIV/00064165:_____/15:10313577
Result on the web
<a href="http://www.biomed.cas.cz/physiolres/pdf/64/64_S203.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/64/64_S203.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The Role of Steroid Hormones in the Development of Intrahepatic Cholestasis of Pregnancy
Original language description
Intrahepatic cholestasis of pregnancy (ICP) is a disorder of liver function, commonly occurring in the third trimester but sometimes also as soon as the end of the second trimester of pregnancy. Symptoms of this disorder include pruritus, plus abnormal values of bile acids and hepatic transaminases. After birth, symptoms disappear and liver function returns to normal. Though ICP is relatively non-complicated and often symptomatically mild from the point-of-view of the mother, it presents a serious riskto the fetus, making this disease the subject of great interest. The etiology and pathogenesis of ICP is multifactorial and as yet not fully elucidated. Hormonal factors likely play a significant role, along with genetic as well as exogenous factors. Here we summarize the knowledge of changes in steroid hormones and their role in the development of intrahepatic cholestasis of pregnancy. In addition, we consider the role of exogenous factors as possible triggers of steroid hormone changes
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT12211" target="_blank" >NT12211: Prediction of termination of pregnancy in women with serious hepatopathies</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physiological Research
ISSN
0862-8408
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
Supplement 2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
"S203"-"S209"
UT code for WoS article
000365011800014
EID of the result in the Scopus database
2-s2.0-84952655118