Feasibility of full and rapid neuromuscular blockade recovery with sugammadex in myasthenia gravis patients undergoing surgery - a series of 117 cases

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10315844" target="_blank" >RIV/00216208:11110/15:10315844 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/15:10315844 RIV/00064203:_____/15:10315844

Result on the web

<a href="http://dx.doi.org/10.2147/TCRM.S93009" target="_blank" >http://dx.doi.org/10.2147/TCRM.S93009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/TCRM.S93009" target="_blank" >10.2147/TCRM.S93009</a>

Result language

angličtina

Original language name

Feasibility of full and rapid neuromuscular blockade recovery with sugammadex in myasthenia gravis patients undergoing surgery - a series of 117 cases

Original language description

Purpose: Myasthenia gravis (MG) is an autoimmune disease interfering with neuromuscular transmission. Patients are at risk of postoperative residual curarization (PORC) if nondepolarizing muscle relaxants are used. Clinically inapparent insufficient muscle strength may result in hypoventilation and postoperative bronchopneumonia. We describe a cohort of 117 cases in which sugammadex was used in MG patients undergoing surgery with muscle relaxation with rocuronium. Methods and patients: We anesthetized 117 patients with MG using rocuronium and sugammadex as neuromuscular blockade reversal agent. One hundred five patients underwent surgical thymectomy and 12 underwent cholecystectomy (five laparotomic and seven laparoscopic). We measured time from sugammadex administration to recovery and to extubation, using the TOF-Watch (R) (series of four consecutive electrical impulses [the train-of-four] >0.9). We tracked peripheral capillary oxygen saturation (SpO(2)) <95%, elevation of partial pr

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

—

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Therapeutics and Clinical Risk Management

ISSN

1178-203X

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

říjen

Country of publishing house

NZ - NEW ZEALAND

Number of pages

4

Pages from-to

1593-1596

UT code for WoS article

000363219700001

EID of the result in the Scopus database

2-s2.0-84945208687