Familial temporal lobe epilepsy due to focal cortical dysplasia type IIIa

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10315986" target="_blank" >RIV/00216208:11110/15:10315986 - isvavai.cz</a>

Alternative codes found

RIV/67985823:_____/15:00448383 RIV/61383082:_____/15:#0000376 RIV/00216208:11130/15:10315986 RIV/00064203:_____/15:10315986

Result on the web

<a href="http://dx.doi.org/10.1016/j.seizure.2015.07.014" target="_blank" >http://dx.doi.org/10.1016/j.seizure.2015.07.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.seizure.2015.07.014" target="_blank" >10.1016/j.seizure.2015.07.014</a>

Result language

angličtina

Original language name

Familial temporal lobe epilepsy due to focal cortical dysplasia type IIIa

Original language description

Purpose: Focal cortical dysplasia (FCD) represents a common cause of refractory epilepsy. It is considered a sporadic disorder, but its occasional familial occurrence suggests the involvement of genetic mechanisms. Methods: Siblings with intractable epilepsy were referred for epilepsy surgery evaluation. Both patients were examined using video-EEG monitoring, MRI examination and PET imaging. They underwent left anteromedial temporal lobe resection. Results: Electroclinical features pointed to left temporal lobe epilepsy and MRI examination revealed typical signs of left-sided hippocampal sclerosis and increased white matter signal intensity in the left temporal pole. PET examination confirmed interictal hypometabolism in the left temporal lobe. Histopathological examination of resected tissue demonstrated the presence FCD type Ilia, i.e. hippocampal sclerosis and focal cortical dysplasia in the left temporal pole. Conclusion: We present a unique case of refractory mesial temporal lobe

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

<a href="/en/project/NT14489" target="_blank" >NT14489: Understanding of functional organization of temporal lobe epilepsy neuronal networks</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Seizure : the journal of the British Epilepsy Association

ISSN

1059-1311

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

září

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

120-123

UT code for WoS article

000361774200021

EID of the result in the Scopus database

2-s2.0-84941137030