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Hippocampal but not amygdalar volume loss in narcolepsy with cataplexy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10322177" target="_blank" >RIV/00216208:11110/15:10322177 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023752:_____/15:43914902 RIV/00064165:_____/15:10322177 RIV/00023884:_____/15:#0007176

  • Result on the web

    <a href="http://www.nel.edu/archive_issues/o/36_7/36_7_Nemcova_682-688.pdf" target="_blank" >http://www.nel.edu/archive_issues/o/36_7/36_7_Nemcova_682-688.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Hippocampal but not amygdalar volume loss in narcolepsy with cataplexy

  • Original language description

    OBJECTIVE: Narcolepsy with cataplexy (NC) and narcolepsy without cataplexy (NwoC) are lifelong neurological disorders characterized primarily by excessive daytime sleepiness. Emotional events such as laughter are a trigger of cataplexy in NC. METHODS: Wecompared the volumes of key limbic structures, the amygdala and hippocampus, in 53 NC, 23 NwoC and 37 control subjects. MRI volumetry was performed in FreeSurfer (FS) and by manual delineation. RESULTS: We found no differences in amygdalar volume in thethree groups, however, hippocampal volume was significantly smaller in the NC group than in other groups. Amygdalar and hippocampal volumes assessed by FS were significantly greater, but strong positive correlation between manual and FS results were observed. Thus, both methods are suitable for amygdalar and hippocampal volumetry.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT13238" target="_blank" >NT13238: Narcolepsy – clinical picture, pathophysiology, ageing, comorbidities and physical activity regimen</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neuroendocrinology Letters

  • ISSN

    0172-780X

  • e-ISSN

  • Volume of the periodical

    36

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    SE - SWEDEN

  • Number of pages

    7

  • Pages from-to

    682-688

  • UT code for WoS article

    000370969000009

  • EID of the result in the Scopus database