Safety and efficacy of endovascular treatment for intracranial infectious aneurysms: A systematic review and meta-analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F16%3A10328390" target="_blank" >RIV/00216208:11110/16:10328390 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.neurad.2016.03.008" target="_blank" >http://dx.doi.org/10.1016/j.neurad.2016.03.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.neurad.2016.03.008" target="_blank" >10.1016/j.neurad.2016.03.008</a>

Result language

angličtina

Original language name

Safety and efficacy of endovascular treatment for intracranial infectious aneurysms: A systematic review and meta-analysis

Original language description

Introduction: Intracranial infectious aneurysms (IIAs), or mycotic aneurysms are rare, representing between 0.7% and 5.4% of all intracranial aneurysms. To clarify the safety and efficacy of endovascular treatment of IIAs, we conducted a systematic review of the literature analyzing periprocedural and long-term clinical and angiographic outcomes. Methods: A comprehensive review of the literature for studies with >= 3 patients related to endovascular treatment of IIAs published through September 2015 was performed. Random effects meta-analysis was used to pool the following outcomes: complete occlusion, technical success, aneurysm recurrence, rebleeding, perioperative mortality, iatrogenic rupture, perioperative stroke, procedure-related morbidity and mortality, long-term neurological morbidity and mortality, and overall good neurological outcome. Results: We included 11 non-comparative studies with 86 target IIAs. Complete occlusion rates were 95.3% (95% CI = 91.2-99.4%). Recurrence occurred in 7.9% (95% CI = 2.7-13.0%). Rebleeding occurred in 5.8% (95% CI = 1.4-10.3%) of patients. Procedure-related morbidity was 12.6% (95% CI = 6.1-19.2%) and procedure-related mortality was 6.1% (95% CI = 1.5-10.8%). Long-term good neurological outcome was 68.0% (95% CI = 55.1-80.9%). Conclusion: Our meta-analysis demonstrated that endovascular treatment is technically feasible and effective with high rates of IIA occlusion. Despite the comorbidities of patients, endovascular approach was associated with acceptable rates of procedure-related morbidity and satisfactory rates of overall good neurological outcome.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neuroradiology

ISSN

0150-9861

e-ISSN

—

Volume of the periodical

43

Issue of the periodical within the volume

5

Country of publishing house

FR - FRANCE

Number of pages

8

Pages from-to

309-316

UT code for WoS article

000385471700002

EID of the result in the Scopus database

2-s2.0-84964644474