Mapping the relationship between clinical and quality-of-life outcomes in patients with ankylosing spondylitis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10337502" target="_blank" >RIV/00216208:11110/17:10337502 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/17:10337502 RIV/00023728:_____/17:N0000056
Result on the web
<a href="http://dx.doi.org/10.1080/14737167.2016.1200468" target="_blank" >http://dx.doi.org/10.1080/14737167.2016.1200468</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/14737167.2016.1200468" target="_blank" >10.1080/14737167.2016.1200468</a>
Alternative languages
Result language
angličtina
Original language name
Mapping the relationship between clinical and quality-of-life outcomes in patients with ankylosing spondylitis
Original language description
AIM: To map health-related quality of life (Qol) with clinical parameters BASFI and ASDAS-CRP measure, and other covariates. METHODS: Our prospective multicenter non-interventional observation study of ankylosing spondylitis (AS) collected data about QoL and clinical outcomes on the initial and four subsequent visits. We employed simple linear regression analysis of a cross-sectional dataset, and fixed effect, random effect and pooled linear regression of a longitudinal dataset. RESULTS: We showed that BASFI and ASDAS-CRP are very strong, robust predictors of EQ-5D utilities in all regression specifications together with sex (female), invalidity, and activity impairment. Additionally, the longitudinal regression analysis showed that a fixed effect model may be a viable alternative to the most commonly used random effect model or pooled linear regression due to the nature of our dataset. CONCLUSION: This is one of the first studies using a fixed effect model in longitudinal patient-level data, although, this method has been widely used in economics.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30226 - Rheumatology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Expert Review of Pharmacoeconomics and Outcomes Research
ISSN
1473-7167
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
2
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
203-211
UT code for WoS article
000399551500010
EID of the result in the Scopus database
2-s2.0-84976313915