Immunonutrition in patients with cyctic fibrosis leads to drop of serum amyloid A and increase of oxidative stress

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10360586" target="_blank" >RIV/00216208:11110/17:10360586 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/17:10360586 RIV/00064203:_____/17:10360586

Result on the web

<a href="https://www.jstage.jst.go.jp/article/jcbn/60/3/60_16-83/_article" target="_blank" >https://www.jstage.jst.go.jp/article/jcbn/60/3/60_16-83/_article</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3164/jcbn.16-83" target="_blank" >10.3164/jcbn.16-83</a>

Result language

angličtina

Original language name

Immunonutrition in patients with cyctic fibrosis leads to drop of serum amyloid A and increase of oxidative stress

Original language description

The aim of the present study is to evaluate of the impact of immunonutrition on parameters of oxidative stress and inflammation in patients with cystic fibrosis and malnutrition. In the 30 patients with cystic fibrosis and long-term enteral nutrition support for malnutrition the effect of standard and immunonutrion sipping on oxidative stress and inflammatory activity parameters was compared. Malonyldialdehyde (MDA) as parameter of oxidative stress and serum amyloid A (SAA), interleukin 1 and 6, hsCRP, IgM, IgA, IgG as parameters of inflammatory activity were examined. Immunonutrition decreased SAA to 17.6 mg/L comparing to 25.6 mg/L when standard nutrition was given (p = 0.014). MDA was 0.66 mu M on standard and 0.96 mu M on immunonutrition support (p &lt; 0.01). The significant negative correlation was recorded between MDA and SAA, hs-CRP, interleukin 6, IgA and IgG. In conclusion, the application of immunonutrition in patients with cystic fibrosis and malnutrition is associated with drop of SAA but with the rise of MDA.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30308 - Nutrition, Dietetics

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Clinical Biochemistry and Nutrition

ISSN

0912-0009

e-ISSN

—

Volume of the periodical

60

Issue of the periodical within the volume

3

Country of publishing house

JP - JAPAN

Number of pages

4

Pages from-to

176-179

UT code for WoS article

000403033800005

EID of the result in the Scopus database

2-s2.0-85019729452