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Decreased Central Nervous System Grey Matter Volume (GMV) in Smokers Affects Cognitive Abilities: A Systematic Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10362291" target="_blank" >RIV/00216208:11110/17:10362291 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/17:10362291

  • Result on the web

    <a href="http://dx.doi.org/10.12659/MSM.901870" target="_blank" >http://dx.doi.org/10.12659/MSM.901870</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.12659/MSM.901870" target="_blank" >10.12659/MSM.901870</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Decreased Central Nervous System Grey Matter Volume (GMV) in Smokers Affects Cognitive Abilities: A Systematic Review

  • Original language description

    Although cigarette smoking is a leading cause of preventable mortality, tobacco is consumed by approximately 22% of the adult population worldwide. Smoking is also a risk factor for cardiovascular disease, affects brain processing, and is a recognized risk factor for Alzheimer disease (AD). Tobacco toxins (e.g., nicotine at high levels) inhaled in smoke may cause disorders resulting in preclinical brain changes. Researchers suggest that there are differences in brain volume between smokers and non-smokers. This review examines these differences in brain grey matter volume (GMV). In March/April 2015, MedLine, Embase, and PsycINFO were searched using the terms: &quot;grey matter&quot; AND &quot;voxel- based&quot; AND &quot;smoking&quot; AND &quot;cigarette&quot;. The 4 studies analyzed found brain GMV decreases in smokers compared to non-smokers. Furthermore, sex-specific differences were found; while the thalamus and cerebellum were affected in both sexes, decreased GMV in the olfactory gyrus was found only in male smokers. Age-group differences were also found, and these may suggest pre-existing abnormalities that lead to nicotine dependence in younger individuals. Only 1 study found a positive correlation between number of pack-years smoked and GMV. Smoking decreases GMV in most brain areas. This decrease may be responsible for the cognitive impairment and difficulties with emotional regulation found in smokers compared with non-smokers.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medical Science Monitor [online]

  • ISSN

    1643-3750

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    April

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    1907-1915

  • UT code for WoS article

    000399566000002

  • EID of the result in the Scopus database

    2-s2.0-85018448385