In vivo study on biodegradable magnesium alloys: Bone healing around WE43 screws
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10369822" target="_blank" >RIV/00216208:11110/18:10369822 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/18:43915367 RIV/00064165:_____/18:10369822
Result on the web
<a href="http://dx.doi.org/10.1177/0885328217743321" target="_blank" >http://dx.doi.org/10.1177/0885328217743321</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/0885328217743321" target="_blank" >10.1177/0885328217743321</a>
Alternative languages
Result language
angličtina
Original language name
In vivo study on biodegradable magnesium alloys: Bone healing around WE43 screws
Original language description
Introduction: A standard osteosynthetic material for maxillofacial skeleton is titanium and its alloys. The convenience of degradable material is avoiding of second surgery in cases, where removal of the material is necessary. Magnesium biodegradable alloys have similar mechanic properties as cortical bone - reasonable corrosion and sufficient biologic properties. They might be used in facial skeleton fixation. Materials and methods: The study included a total of 16 rabbits, and they were randomly divided into two groups. Each group received two screws (WE4 and titanium as a standard material) in artificially drilled defect into right tibia. Animals were euthanized at four-week intervals. Bone samples with implants underwent microfocus CT scans and were histologically examined. Results: WE43 alloys showed fragmentation of the material on the 16th week - statistically significant volume loss was found between weeks 12 and 16. Bone healing around the WE43 screws was of similar quality as around titanium screws, and no adverse effect was noticed. Conclusion: The study showed good quality of bone healing around WE43 implants. From this point of view, the WE43 alloy meets the requirements of osteosynthetic material for maxillofacial skeleton.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10600 - Biological sciences
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Biomaterials Applications
ISSN
0885-3282
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
7
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
886-895
UT code for WoS article
000419897400005
EID of the result in the Scopus database
2-s2.0-85040640526