Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23 weeks' gestation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10371144" target="_blank" >RIV/00216208:11110/18:10371144 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/18:43916168 RIV/00064165:_____/18:10371144

Result on the web

<a href="http://dx.doi.org/10.1515/jpm-2016-0264" target="_blank" >http://dx.doi.org/10.1515/jpm-2016-0264</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/jpm-2016-0264" target="_blank" >10.1515/jpm-2016-0264</a>

Result language

angličtina

Original language name

Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23 weeks' gestation

Original language description

Objective: The aim of this single-center study was to identify factors that affect the short-term outcome of newborns delivered around the limits of viability. Methods: A group of 137 pregnant women who gave birth between 22+0/7 and 25+6/7 weeks of gestation was retrospectively studied. The center supports a proactive approach to infants around the limits of viability. Perinatal and neonatal characteristics were obtained and statistically evaluated. Results: A total of 166 live-born infants were enrolled during a 6-year period; 162 (97.6%) of them were admitted to the neonatal intensive care unit (ICU) and 119 (73.5%) survived until discharge. The decrease in neonatal mortality was associated with an advanced gestational age (P&lt;0.001) and a completed course of corticosteroids (P=0.002). Neonatal morbidities were common among infants of all gestational ages. The incidence of severe intraventricular hemorrhage significantly depended on gestational age (P&lt;0.001) and a completed course of corticosteroids (P=0.002). Survival without severe neonatal morbidities was 39.5% and occurred mostly after 24+0/7 weeks of gestation. Conclusion: The short-term outcome of newborns delivered around the limits of viability is mostly affected by gestational age and antenatal corticosteroid treatment. A consistently proactive approach improves the survival of infants at the limits of viability. This is most pronounced in cases where the delivery is delayed beyond 24 completed gestational weeks.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30214 - Obstetrics and gynaecology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Perinatal Medicine

ISSN

0300-5577

e-ISSN

—

Volume of the periodical

46

Issue of the periodical within the volume

1

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

103-111

UT code for WoS article

000419583300014

EID of the result in the Scopus database

2-s2.0-85041479489