Maternal and obstetrical outcome in 35 cases of well-differentiated thyroid carcinoma during pregnancy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10375860" target="_blank" >RIV/00216208:11110/18:10375860 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/18:43915651 RIV/00064173:_____/18:N0000089 RIV/00064203:_____/18:10375860

Result on the web

<a href="https://doi.org/10.1002/lary.26936" target="_blank" >https://doi.org/10.1002/lary.26936</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/lary.26936" target="_blank" >10.1002/lary.26936</a>

Result language

angličtina

Original language name

Maternal and obstetrical outcome in 35 cases of well-differentiated thyroid carcinoma during pregnancy

Original language description

Objectives/Hypothesis: Thyroid cancer, with 6% to 10% of cancer diagnoses, is one of the most common malignancies during pregnancy. Its treatment poses a risk for the pregnancy, as the thyroid gland plays a crucial role in the evolution of pregnancy. The aim of this study is to evaluate treatment of primary well-differentiated thyroid carcinoma during pregnancy and fetal and maternal outcomes. Study Design: This is an international cohort study. Methods: Primary thyroid cancer patients were identified from the database of the International Network on Cancer, Infertility, and Pregnancy registration study. Data on histopathological characteristics, diagnostic and therapeutic interventions, outcome (obstetrical, neonatal, and maternal) and maternal follow-up were analyzed. Results: Thirty-five patients with well-differentiated thyroid carcinoma were eligible. All 35 patients underwent surgery, 29 (83%) of which during pregnancy. Procedures during pregnancy were mainly total thyroidectomies (n = 24). The median number of days between diagnosis and surgical treatment was different between the groups with surgery during and after pregnancy (27 vs. 139 days, P &lt;.001). Both maternal and neonatal outcomes were uncomplicated, regardless of gestational age during surgery. Conclusions: Well-differentiated thyroid carcinoma diagnosed during pregnancy has a favorable outcome for both mother and child. Surgical management during pregnancy has no negative impact on the pregnancy regardless of the trimester at the time of surgery. However, the potential negative effects of thyroid surgery early in pregnancy demand management of these patients in an experienced multidisciplinary team to provide the best possible care for these patients and their unborn babies. Level of Evidence: 4. Laryngoscope, 128:1493-1500, 2018.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30206 - Otorhinolaryngology

Project

<a href="/en/project/NV15-28933A" target="_blank" >NV15-28933A: Tumor microenvironment of head and neck carcinoma: Prognostic significance of extracellular matrix produced by tumor-associated fibroblasts</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Laryngoscope

ISSN

0023-852X

e-ISSN

—

Volume of the periodical

128

Issue of the periodical within the volume

6

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

1493-1500

UT code for WoS article

000434179100046

EID of the result in the Scopus database

2-s2.0-85030652417