Late relapse in stage I of nonseminomatous germ cell testicular cancer on surveillance
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10376437" target="_blank" >RIV/00216208:11110/18:10376437 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.4149/BLL_2018_001" target="_blank" >https://doi.org/10.4149/BLL_2018_001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/BLL_2018_001" target="_blank" >10.4149/BLL_2018_001</a>
Alternative languages
Result language
angličtina
Original language name
Late relapse in stage I of nonseminomatous germ cell testicular cancer on surveillance
Original language description
OBJECTIVE: Primary aim was to assess relapse-free survival (RFS) in patients with clinical stage I (CS I) of non-seminomatous germ cell testicular tumors (NSGCTT) undergoing surveillance after orchiectomy. The secondary aim was to examine differences in risk factors in patients with early relapse (ER < 2 years), late relapse (LR > 2 years) and very late relapse (VLR > 5 years). METHODS: Cross-sectional study analyzed 25-year single-center experiences with 198 CS I NSGCTT patients according the time to relapse. RESULTS: RFS was 160/198 (80.8 %). Relapse occurred in 38 (19.2 %) patients after a median follow-up of 7.57 months, 33 (86.8 %) patients had ER after a median follow-up of 7.03 months and 5 patients had LR (13.2 %) after a median follow-up of 26.28 months. One patient (2.63 %) had VLR after follow-up > 5 years (7.17 years). Three relapsed patients died with metastatic disease after a mean follow-up of 5.1 years from the date of diagnosis. Another three patients died without cancer after a mean follow-up of two years. OS was 192/198 (97 %). CONCLUSION: Diagnosis and treatment of late relapsing NSGCTT patients should be performed in experienced centers only. Occurrence of LR is the reason for long-term monitoring of NSGCTT survivors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bratislavské lekárske listy
ISSN
0006-9248
e-ISSN
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Volume of the periodical
119
Issue of the periodical within the volume
1
Country of publishing house
SK - SLOVAKIA
Number of pages
3
Pages from-to
3-5
UT code for WoS article
000425181900001
EID of the result in the Scopus database
2-s2.0-85042108919