Localization of ventricular activation origin using patient-specific geometry: Preliminary results

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10377119" target="_blank" >RIV/00216208:11110/18:10377119 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/18:10377119

Result on the web

<a href="https://doi.org/10.1111/jce.13622" target="_blank" >https://doi.org/10.1111/jce.13622</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jce.13622" target="_blank" >10.1111/jce.13622</a>

Result language

angličtina

Original language name

Localization of ventricular activation origin using patient-specific geometry: Preliminary results

Original language description

Background and objectives: Catheter ablation of ventricular tachycardia (VT) may include induction of VT and localization of VT-exit site. Our aim was to assess localization performance of a novel statistical pace-mapping method and compare it with performance of an electrocardiographic inverse solution. Methods: Seven patients undergoing ablation of VT (4 with epicardial, 3 with endocardial exit) aided by electroanatomic mapping underwent intraprocedural 120-lead body-surface potential mapping (BSPM). Two approaches to localization of activation origin were tested: (1) A statistical method, based on multiple linear regression (MLR), which required only the conventional 12-lead ECGfor a sufficient number of pacing siteswith known origin together with patient-specific geometry of the endocardial/epicardial surface obtained by electroanatomicmapping; and (2) a classical deterministic inverse solution for recovering heart-surface potentials, which required BSPM and patient-specific geometry of the heart and torso obtained via computed tomography (CT). Results: For the MLR method, at least 10-15 pacing sites with known coordinates, together with their corresponding 12-lead ECGs, were required to derive reliable patient-specific regression equations, which then enabled accurate localization of ventricular activation with unknown origin. For 4 patients who underwent epicardial mapping, the median of localization error for the MLR was significantly lower than that for the inverse solution (10.6 vs. 27.3 mm, P = 0.034); a similar result held for 3 patients who underwent endocardial mapping (7.7 vs. 17.1 mm, P = 0.017). The pooled localization error for all epicardial and endocardial sites was also significantly smaller for theMLR compared with the inverse solution (P = 0.005). Conclusions: The novel pace-mapping approach to localizing the origin of ventricular activation offers an easily implementable supplement and/or alternative to the preprocedure inverse solution; its simplicity makes it suitable for real-time applications during clinical catheter-ablation procedures.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Cardiovascular Electrophysiology

ISSN

1045-3873

e-ISSN

—

Volume of the periodical

29

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

979-986

UT code for WoS article

000437739600009

EID of the result in the Scopus database

2-s2.0-85047617822