Alzheimer's disease and blood-based biomarkers - potential contexts of use
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10377524" target="_blank" >RIV/00216208:11110/18:10377524 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/18:10377524
Result on the web
<a href="https://doi.org/10.2147/NDT.S172285" target="_blank" >https://doi.org/10.2147/NDT.S172285</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/NDT.S172285" target="_blank" >10.2147/NDT.S172285</a>
Alternative languages
Result language
angličtina
Original language name
Alzheimer's disease and blood-based biomarkers - potential contexts of use
Original language description
Alzheimer's disease (AD) is an irreversible, incurable, progressive neurodegenerative illness, where dementia symptoms gradually worsen over a number of years. The research of validated biomarkers for AD is essential to improve diagnosis and accelerate the development of new therapies. Biochemical markers including neuroimaging could facilitate diagnosis, predict AD progression from a pre-AD state of mild cognitive impairment, and be used to detect the efficacies of disease-modifying therapies. Established biomarkers of AD from cerebrospinal fluid and neuroimaging are highly accurate, but barriers to clinical implementation exist. The focus on blood-based AD biomarkers has grown exponentially during the past few decades. An ideal diagnostic test for AD should be noninvasive and easily applicable. Clinical cost-effectiveness also needs to be established.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
<a href="/en/project/GA17-05292S" target="_blank" >GA17-05292S: Novel blood-based biomarkers for early diagnosis, prognosis and progress of Alzheimer's disease</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuropsychiatric Disease and Treatment
ISSN
1178-2021
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
July
Country of publishing house
NZ - NEW ZEALAND
Number of pages
6
Pages from-to
1877-1882
UT code for WoS article
000439511300002
EID of the result in the Scopus database
2-s2.0-85057543947