Dissociative states in borderline personality disorder and their relationships to psychotropic medication

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10385129" target="_blank" >RIV/00216208:11110/18:10385129 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/18:00106588

Result on the web

<a href="https://doi.org/10.2147/NDT.S179091" target="_blank" >https://doi.org/10.2147/NDT.S179091</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/NDT.S179091" target="_blank" >10.2147/NDT.S179091</a>

Result language

angličtina

Original language name

Dissociative states in borderline personality disorder and their relationships to psychotropic medication

Original language description

Background: According to recent data, dissociation may play an important role in borderline personality disorder (BPD), nevertheless specific influences of psychotropic medication on dissociative symptoms in BPD and their therapeutic indications are largely unknown. The purpose of this study was to assess relationships of dissociative symptoms in BPD patients with levels of psychotropic medication and compare these results with a subgroup of patients with schizophrenia. Materials and methods: In this study, we investigated 52 BPD patients and compared the results with a control group of 36 schizophrenia patients. In all participants, we assessed actual day doses of antipsychotic medication in chlorpromazine equivalents and antidepressant medication in fluoxetine equivalents. Dissociative symptoms were measured by Dissociative Experiences Scale (DES), and other psychopathological symptoms were measured using Health of the Nation Outcome Scales. Results: Results indicate that dissociative symptoms measured by DES were significantly correlated with antipsychotic medication (Spearman R=0.45, P&lt;0.01) in chlorpromazine equivalents and antidepressant medication in fluoxetine equivalents (0.36, P&lt;0.01). These relationships between medication and dissociative symptoms were not found in the control group of schizophrenia patients. Conclusion: The results suggest that levels of antipsychotic medication and antidepressant medication are significantly associated with dissociative symptoms in BPD but not in schizophrenia.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30215 - Psychiatry

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuropsychiatric Disease and Treatment

ISSN

1178-2021

e-ISSN

—

Volume of the periodical

14

Issue of the periodical within the volume

November

Country of publishing house

NZ - NEW ZEALAND

Number of pages

5

Pages from-to

3253-3257

UT code for WoS article

000451245400002

EID of the result in the Scopus database

2-s2.0-85057541219