Transection of inferior alveolar nerve in the rat - neuroanatomical study and experimental model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10411365" target="_blank" >RIV/00216208:11110/18:10411365 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/18:S0002005 RIV/00064165:_____/18:10411365
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=RUOv6p~7ql" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=RUOv6p~7ql</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Transection of inferior alveolar nerve in the rat - neuroanatomical study and experimental model
Original language description
Objective. Experimental lesions in the inferior alveolar nerve (IAN) are used for the study of peripheral and central alterations. The objective of our study was to contribute to a more precise description of the approach to the IAN and creating a lesion. Material and methods. Twenty-six males of Wistar laboratory rats were used for the study. The animals were divided into three groups: control group (6 rats), experimental group (12 rats - a part of the bone above the mandibular canal was removed under general anaesthesia using extraoral approach, after exposing a part of the IAN, the nerve was excised in a length of 3 mm), and a sham group (8 rats - the nerve was only dissected but not transected). Persisting denervation was verified using surgical revision and histological and immunohistochemical analysis after the observation period (4 weeks). Results. No evidence of re-innervation after 4 weeks. We found no statistically significant differences in mean weight gains between individual groups during the observation period. Conclusion. The described technique used in the study is one of the possible ways to create a nerve lesion at the site of the main trunk of the nerve. At the same time, the study provides a more precise description of the anatomical situation and approach to the IAN in the mandibular canal. (C) 2018, Czech Medical Association J.E. Purkyne. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30212 - Surgery
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Chirurgiae Plasticae
ISSN
0001-5423
e-ISSN
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Volume of the periodical
60
Issue of the periodical within the volume
2-4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
48-53
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85084328932