Assessment of renal function before contrast media injection: right decisions based on inaccurate estimates

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F19%3A10388223" target="_blank" >RIV/00216208:11110/19:10388223 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/19:10388223

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5Jv2cVlcvp" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5Jv2cVlcvp</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00330-018-5753-z" target="_blank" >10.1007/s00330-018-5753-z</a>

Result language

angličtina

Original language name

Assessment of renal function before contrast media injection: right decisions based on inaccurate estimates

Original language description

Objectives: Information on renal function required before specified radiological examinations with contrast agents is usually obtained through prediction equations using serum creatinine and anthropometric data. The aim of our study was to demonstrate discrepancy between poor prediction and good diagnostic accuracy of glomerular filtration rate (GFR) estimated by prediction equations. Methods: In 50 patients, reference GFR was measured as plasma clearance of 51-chromium labeled ethylene-diamine-tetraacetic-acid (51Cr-EDTA) and compared with GFR assayed by creatinine clearance (CC) and estimated by Cockcroft-Gault prediction equation (CG). For comparisons, CC and CG were considered as continuous, categorical, and binary variables. Accuracy of the reference GFR prediction was expressed in terms of prediction errors and diagnostic accuracy indices. Results: As continuous variable, CG estimated individual values of GFR with large prediction error exceeding that of CC. As categorical variable, it classified the patient stage of chronic kidney disease (CKD) with medium diagnostic accuracy of 74% (CKD 3) and 62% (CKD 4). As binary variable, CG classified individual patient&apos;s GFR below 30 and 60 ml/min/1.73 m2 with good diagnostic accuracy of 80 and 94%, respectively. Performance of other prediction equations did not significantly differ from CG. Conclusions: Despite large variance and poor prediction accuracy of individual GFR estimates, most of them correctly classified individual patient&apos;s GFR below specified level. Results of prediction equations thus should be used and reported exclusively as binary variables, while numerical values of GFR, if required, should be measured by more accurate radionuclide or laboratory methods.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

<a href="/en/project/GA303%2F07%2F0950" target="_blank" >GA303/07/0950: Quantitative assessment of dynamic renal scintigraphy</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Radiology

ISSN

0938-7994

e-ISSN

—

Volume of the periodical

29

Issue of the periodical within the volume

6

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

3192-3199

UT code for WoS article

000467646300047

EID of the result in the Scopus database

2-s2.0-85056335288