Olfactory results of endoscopic endonasal surgery for pituitary adenoma: A prospective study of 143 patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F19%3A10394080" target="_blank" >RIV/00216208:11110/19:10394080 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/19:43918240 RIV/61383082:_____/19:00000491

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ufPMW7SJmK" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ufPMW7SJmK</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.wneu.2019.05.061" target="_blank" >10.1016/j.wneu.2019.05.061</a>

Result language

angličtina

Original language name

Olfactory results of endoscopic endonasal surgery for pituitary adenoma: A prospective study of 143 patients

Original language description

BACKGROUND: Clinical examination, including pre- and postoperative assessment of olfaction function, should be included in evaluating surgical outcomes in patients with pituitary adenomas. Most of the studies are lacking assessment of olfactory function. METHODS: A prospective study with 143 patients who underwent surgical resection of pituitary adenomas from January 2014 to December 2017 was performed. Data on clinical presentation, pre- and postoperative neurologic, endocrinologic and ophthalmologic examinations, complications and follow-up outpatient examinations were recorded. Olfactory function was assessed using the Sniffin&apos; Sticks odor identification test preoperatively, postoperatively (3 months) and 1 year after surgery. RESULTS: Normosmia was present preoperatively in 93.7% of the patients, postoperatively in 95.8% and in 95.1% 1 year post-surgery. Hyposmia was present preoperatively in 4.2% of the patients, postoperatively in 2.1% and in 1.4% 1 year after surgery. Anosmia was present preoperatively in 2.1% of the patients, postoperatively in 2.1% and in 3.5% 1 year after surgery. In patients with preoperative normosmia postoperative hyposmia and anosmia were present in 1.5% of the patients. There were no differences according to age, gender, size or type of pituitary adenoma. CONCLUSIONS: Assessment of olfactory function should be included in the analysis of pituitary adenoma surgery results. This prospective study showed low risk of olfaction deterioration if an endoscopic endonasal approach is used without any mucosal flaps for skull base reconstruction. Further studies that include objective olfaction assessment are warranted.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30206 - Otorhinolaryngology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

World Neurosurgery

ISSN

1878-8750

e-ISSN

—

Volume of the periodical

129

Issue of the periodical within the volume

September

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

"e907"-"e914"

UT code for WoS article

000481607900113

EID of the result in the Scopus database

2-s2.0-85067874366