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Pigments from Filamentous Ascomycetes for Combination Therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F19%3A10400599" target="_blank" >RIV/00216208:11110/19:10400599 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027022:_____/18:N0000011 RIV/60461373:22340/19:43919261 RIV/00064165:_____/19:10400599

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Y~0zlp2UwN" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Y~0zlp2UwN</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2174/0929867325666180330091933" target="_blank" >10.2174/0929867325666180330091933</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Pigments from Filamentous Ascomycetes for Combination Therapy

  • Original language description

    Filamentous ascomycetes (Neurospora and Monascus) have been studied for a long time because of their production of secondary metabolites such as microbial pigments. The ascomycetes represent an interesting group of compounds with high potential for medicinal applications. Many recent studies have shown their efficacy in the treatment of serious pathological states such as oncological diseases, neurodegenerative diseases and hyperlipidaemia. Nevertheless, the clinical usability of ascomycetes is still limited. However, this problem can be solved by the use of these compounds with combinations of other therapeutic agents. This strategy can suppress their side effects and improve their therapeutic efficacy. Moreover, their co-application can significantly enhance conventional therapies that are used. This review summarizes and discusses the general principles of this approach, introduced and supported by numerous examples. In addition, the prediction of the future potential application of this methodology is included.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    <a href="/en/project/FV20572" target="_blank" >FV20572: Adjuvant therapy</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Current Medicinal Chemistry

  • ISSN

    0929-8673

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    20

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    23

  • Pages from-to

    3812-3834

  • UT code for WoS article

    000485822100010

  • EID of the result in the Scopus database

    2-s2.0-85072600023