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Combined use of galectin-3 and thyroid peroxidase improves the differential diagnosis of thyroid tumors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F20%3A10405818" target="_blank" >RIV/00216208:11110/20:10405818 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064203:_____/20:10405818 RIV/00216208:11140/20:10405818 RIV/00669806:_____/20:10405818

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=WXN_L4jhRm" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=WXN_L4jhRm</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4149/neo_2019_190128N86" target="_blank" >10.4149/neo_2019_190128N86</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Combined use of galectin-3 and thyroid peroxidase improves the differential diagnosis of thyroid tumors

  • Original language description

    The study was focused on the assessment of an expression of galectin-3 and thyroid peroxidase (TPO) in a large collection of 186 thyroid tumors, benign and malignant and their oncocytic and non-oncocytic variants. Oncocytic tumors remain controversial with a respect to their pathobiology, behavior and management. The aim of this study was to evaluate the differential diagnostic/prognostic potential of both markers . In conclusion, the combined use of galectin-3 and TPO markers could help to improve the differential diagnosis of malignant thyroid tumors, whereas the use them as a single marker remains unsatisfactory. Differences in expression of both markers between oncocytic and non-oncocytic variants is another argument for an explanation of their differing pathobiology and their separation in independent neoplastic entities.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30206 - Otorhinolaryngology

Result continuities

  • Project

    <a href="/en/project/GA18-03978S" target="_blank" >GA18-03978S: Effect of cell stiffness and microenvironment as a therapy response predictor in head and neck cancer</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neoplasma

  • ISSN

    0028-2685

  • e-ISSN

  • Volume of the periodical

    67

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    7

  • Pages from-to

    164-170

  • UT code for WoS article

    000542659200019

  • EID of the result in the Scopus database

    2-s2.0-85078691434