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Drug dosing in cancer patients with decreased kidney function: A practical approach

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F21%3A10424131" target="_blank" >RIV/00216208:11110/21:10424131 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/21:10424131

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ioSYcYfHOk" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ioSYcYfHOk</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ctrv.2020.102139" target="_blank" >10.1016/j.ctrv.2020.102139</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Drug dosing in cancer patients with decreased kidney function: A practical approach

  • Original language description

    Correct drug dosing of anticancer agents is essential to obtain optimal outcomes. Overdosing will result in increased toxicity, treatment interruption and possible cessation of anticancer treatment. Underdosing may result in suboptimal anti-cancer effects and may increase the risk of cancer-related mortality. As it is practical nor feasible to perform therapeutic drug monitoring for all anti-cancer drugs, kidney function is used to guide drug dosing for those drugs whose primary mode of excretion is through the kidney. However, it is not well-established what method should be utilized to measure or estimate kidney function and the choice of method does influence treatment decisions regarding eligibility for anti-cancer drugs and their dose. In this review, we will provide an overview regarding the importance of drug dosing, the preferred method to determine kidney function and a practical approach to drug dosing of anticancer drugs.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30217 - Urology and nephrology

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cancer Treatment Reviews

  • ISSN

    0305-7372

  • e-ISSN

  • Volume of the periodical

    93

  • Issue of the periodical within the volume

    February

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    102139

  • UT code for WoS article

    000618657200003

  • EID of the result in the Scopus database

    2-s2.0-85098724925