Pentamethinium Salts Nanocomposite for Electrochemical Detection of Heparin
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F21%3A10433413" target="_blank" >RIV/00216208:11110/21:10433413 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22340/21:43922025
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=iMSX5VuPml" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=iMSX5VuPml</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ma14185357" target="_blank" >10.3390/ma14185357</a>
Alternative languages
Result language
angličtina
Original language name
Pentamethinium Salts Nanocomposite for Electrochemical Detection of Heparin
Original language description
This study presents a simple route to heparin detection and develops a voltammetric approach using supramolecular principles and nanomaterials. Nanocomposites, including gold nanoparticles (AuNPs) and gamma-substituted pentamethinium salts (PMS) deposited on a glass carbon (GC) electrode surface (GC/AuNPs/PMS) and covered by a plasticized poly(vinyl chloride) (PVC) membrane, are proposed for heparin detection. The conductivity of the nonconducting PVC-plasticized membrane is guaranteed by AuNPs, and the selectivity is provided by the interaction between gamma-substituted PMS and anionic analytes. In order to extend the linear range, it is necessary to apply a solvent compatible with PVC-plasticized membrane, namely tetrahydrofuran. The proposed voltammetric sensor showed a concentration dependence from 1.72 up to 45.02 IU mL(-1) heparin and was used for heparin detection in saline and biological samples with recovery of 95.1-100.9%.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials [online]
ISSN
1996-1944
e-ISSN
—
Volume of the periodical
14
Issue of the periodical within the volume
18
Country of publishing house
CH - SWITZERLAND
Number of pages
10
Pages from-to
5357
UT code for WoS article
000700742300001
EID of the result in the Scopus database
2-s2.0-85115293947