On the role of sex steroids in biological functions by classical and non-classical pathways. An update
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F21%3A10433465" target="_blank" >RIV/00216208:11110/21:10433465 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=nvdTOLORhj" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=nvdTOLORhj</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.yfrne.2021.100926" target="_blank" >10.1016/j.yfrne.2021.100926</a>
Alternative languages
Result language
angličtina
Original language name
On the role of sex steroids in biological functions by classical and non-classical pathways. An update
Original language description
The sex steroid hormones (SSHs) play several roles in regulation of various processes in the cardiovascular, immune, muscular and neural systems. SSHs affect prenatal and postnatal development of various brain structures, including regions associated with important physiological, behavioral, cognitive, and emotional functions. This action can be mediated by either intracellular or transmembrane receptors. While the classical mechanisms of SSHs action are relatively well examined, the physiological importance of non-classical mechanism of SSHs action through membrane-associated and transmembrane receptors in the brain remains unclear. The most recent summary describing the role of SSHs in different body systems is lacking. Therefore, the aim of this review is to discuss classical and non-classical signaling pathways of testosterone and estradiol action via their receptors at functional, cellular, tissue level and to describe the effects on various body systems and behavior. Particular emphasis will be on brain regions including the hippocampus, hypothalamus, frontal cortex and cerebellum.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30105 - Physiology (including cytology)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Neuroendocrinology
ISSN
0091-3022
e-ISSN
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Volume of the periodical
62
Issue of the periodical within the volume
July
Country of publishing house
US - UNITED STATES
Number of pages
18
Pages from-to
100926
UT code for WoS article
000701618700008
EID of the result in the Scopus database
2-s2.0-85107701256