Chronic kidney disease and pregnancy outcomes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F21%3A10434398" target="_blank" >RIV/00216208:11110/21:10434398 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/21:10434398

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=osEb4e7lW3" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=osEb4e7lW3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-021-00670-3" target="_blank" >10.1038/s41598-021-00670-3</a>

Result language

angličtina

Original language name

Chronic kidney disease and pregnancy outcomes

Original language description

Pregnancy complicated by CKD is currently not fully understood topic. Outcome of pregnancy in patients with CKD is related to impaired glomerular filtration rate and the degree of proteinuria. In our study we evaluated the association of serum creatinine level and proteinuria with both maternal and fetal outcomes in the cohort of 84 pregnant patients with CKD. In CKD group we confirmed negative correlation of highest serum creatinine level in pregnancy to fetal weight (p value &lt; 0.001) and gestation period (p value &lt; 0.001). Likewise, negative correlation of preconception serum creatinine to fetal weight (p value &lt; 0.001) and gestation period (p value 0.002). Negative correlation of proteinuria to gestation period (p value &lt; 0.001) and fetal weight (p value &lt; 0.001) was also demonstrated. CKD is serious risk factor for pregnancy outcome. Proteinuria and serum creatinine level should be examined before pregnancy and regularly monitored during pregnancy. Higher serum creatinine levels and higher proteinuria predispose to shorter gestation period and lower birth weight of the neonate.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30217 - Urology and nephrology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scientific Reports

ISSN

2045-2322

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

21299

UT code for WoS article

000712891800028

EID of the result in the Scopus database

2-s2.0-85118444516