Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F01%3A00110191" target="_blank" >RIV/00216208:11120/01:00110191 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Comparison of mutagenicity of selected natural chemical compounds in different tests for testing of mutagenicity
Original language description
Mutagenic, antimutagenic and immunomodulatory effects of plant compounds were studied in procaryotic (Salmonella typhimurium) and eucaryotic (male BALB C mice) models. Strong antimutagenic effect against AFB1 was found in cauliflower, carrot and garlic extracts. Extracts from cauliflower and carrot was also able significantly increase extremly low levels of chemiluminescence and blastic transformation, caused by AFB1 and heterocyclic amines from protein pyrolyzate. Some plant compounds (-angelikalactone, juglone, humulone, emodine, hypericine, psoralene) revealed mutagenic activity. Strong antimutagenic effect of plant phenol ellagic acid against mutagenicity of AFB1 and amino-methylimidazo-quinoline (IQ) were detected in Ames and micronucleus tests.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2001
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Abstracts of Federazione Italiana Scienze della Vita
ISBN
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ISSN
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e-ISSN
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Number of pages
3
Pages from-to
15-11
Publisher name
FISV
Place of publication
Riva del Garda
Event location
Riva del Garda
Event date
Jan 1, 2001
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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