Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F03%3A00007497" target="_blank" >RIV/00216208:11120/03:00007497 - isvavai.cz</a>

Alternative codes found

RIV/00023752:_____/03:00000320

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report)

Original language description

Objective: This paper presents functional magnetic resonance imaging (fMRI) and magnetic resonance spectroscopy (MRS) findings in a monozygotic twin pair discordant for schizophrenia. Method: Functional magnetic resonance imaging was used to determine hemispheric lateralization for speech and proton MRS (1H-MRS) was employed to assess the extent of putative insult to anterior hippocampus. Results: Despite concordant right handedness, subject with schizophrenia displayed bilateral activation in areas subserving speech with greater extent of the total activated area compared with the healthy twin. The affected twin displayed relative bilateral decrease in N-acetylaspartate/creatin concentration in the anterior hippocampus compared with the healthy one.Conclusion: This is an evidence for non-genetic impairment of cerebral lateralization in monozygotic twin with schizophrenia.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FL - Psychiatry, sexology

OECD FORD branch

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Project

<a href="/en/project/NF6794" target="_blank" >NF6794: Hippocampal impairment in schizophrenia: proton magnetic resonance spectroscopy study and dermatoglyphic analysis</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Psychiatrica Scandinavica

ISSN

0001-690X

e-ISSN

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Volume of the periodical

107

Issue of the periodical within the volume

2

Country of publishing house

DK - DENMARK

Number of pages

4

Pages from-to

155-158

UT code for WoS article

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EID of the result in the Scopus database

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