Use of recombinant activated factor VII in cardiac surgery for an effective treatment of severe intractable bleeding

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F04%3A00000974" target="_blank" >RIV/00216208:11120/04:00000974 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Use of recombinant activated factor VII in cardiac surgery for an effective treatment of severe intractable bleeding

Original language description

Experience gained with administration of Supranormal-therapeutic doses (90 mug/kg) of recombinant activated factor VII in 7 cardiac surgery patients is presented. The patients were given recombinant activated factor VII postoperatively for intractable bleeding, 5 of them after surgical revision. Administration of recombinant activated factor VII was associated with significant reduction in blood loss (P < 0.05) and shortening of INR and aPTT in laboratory tests. None of the patients needed reoperation.Administration of recombinant activated factor VII proved highly effective in management of massive hemorrhage in cardiac surgery

Czech name

Užití rekombinantního aktivačního faktoru VII v kardiochirurgii pro efektivní léčbu vážného nezzvaldatelného krvácení

Czech description

práce popisuje užití rekombinantního aktivačního faktoru VII v kardiochirurgii pro efektivní léčbu vážného nezzvaldatelného krvácení

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2004

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Japanese Heart Journal

ISSN

0021-4868

e-ISSN

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Volume of the periodical

45

Issue of the periodical within the volume

5

Country of publishing house

JP - JAPAN

Number of pages

6

Pages from-to

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UT code for WoS article

000226083000014

EID of the result in the Scopus database

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