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Effects of anesthesia and nociceptive stimulation in an experimental model of brachial plexus avulsion

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F04%3A00001112" target="_blank" >RIV/00216208:11120/04:00001112 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21460/04:12141092

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effects of anesthesia and nociceptive stimulation in an experimental model of brachial plexus avulsion

  • Original language description

    Extensive dorsal rhizotomy of brachial plexus, which is used as a model of deafferentational pain, performed under ketamine anesthesia in rats do not result in development of selfmutilation. This effect might be suppressed by short period of nociceptivestimulation of the limb just before the induction into anesthesia. These results suggest crucial role of anesthesia involving NMDA receptors, and the role of injury discharge in the model.

  • Czech name

    Vliv anestezie a nocicepční stimulace u modelu avulze brachiálního plexu

  • Czech description

    Extenzivní dorzální rizotomie brachiálního plexu je používána jako model deaferentační bolesti. Provede-li se v ketaminové anestezii, bolestivý syndrom se nerozvine, pokud se před anestetií tlapka nociceptivně stimuluje, bolest se rozvíjí. Výsledky ukazují zapojení NMDA receptorů do rozvoje neuropatické bolesti a zdůrazňují roli výboje z poranění.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LN00B122" target="_blank" >LN00B122: Neuropsychiatric Research Center</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Research

  • ISSN

    0862-8408

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    209-214

  • UT code for WoS article

  • EID of the result in the Scopus database