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Physiological regulation of NEFA availability: lipolysis pathway

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F04%3A00001135" target="_blank" >RIV/00216208:11120/04:00001135 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Physiological regulation of NEFA availability: lipolysis pathway

  • Original language description

    Plasma NEFA are an important energy substrate and, furthermore, play a key role in the induction of insulin resistance in the body. The availability of NEFA is determined predominantly by their mobilization from adipose tissue triacylglycerol stores by the process of lipolysis. Adipose tissue lipolysis in man is regulated by a number of hormonal and paracrine and/or autocrine signals. The main hormonal signals may be represented by catecholamines, insulin, growth hormone, natriuretic peptides and some adipocytokines. The absolute levels and relative importance and contribution of these signals vary in different physiological situations, with diet and physical exercise being the main physiological variables that affect the hormonal signalling. Thus, modulations in hormonal signals induce an increase in NEFA mobilization in the post-absorptive state and during an acute bout of exercise, and suppress NEFA mobilization in the postprandial state.

  • Czech name

    Fyziologická regulace dostupnosti VMK: lipolytická cesta

  • Czech description

    VMK hrají klíčovou roli při vzniku inzulínové rezistence. Dostupnost VMK je dána především jejich mobilizací ztukové tkáně. Jsou popisovány regulační mechanizmy lipolýzy tukové tkáně (hormonální, parakrinní a autokrinní signály) a možnosti ovlivnění těchto mechanizmů (energetický příjem , tělesné cvičení, trénink).

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NB6836" target="_blank" >NB6836: Dynamic resistance training in the treatment of metabolic syndrom</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nutrition Society. Proceedings

  • ISSN

    0029-6651

  • e-ISSN

  • Volume of the periodical

    63

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    369-374

  • UT code for WoS article

  • EID of the result in the Scopus database