Effect of endurance training on adrenergic control of lipolysis in adipose tissue of obese women
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F04%3A00001136" target="_blank" >RIV/00216208:11120/04:00001136 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of endurance training on adrenergic control of lipolysis in adipose tissue of obese women
Original language description
The effect of a 12-wk training program on sc abdominal adipose tissue (SCAAT) was studied in 11 obese women. Before and after the training, biopsies of SCAAT were performed for mRNA levels determination. Using the microdialysis method, involvement of alpha(2)- and beta-adrenergic receptor (ARs) in the control of lipolysis in SCAAT was studied using local perfusion of epinephrine alone or supplemented with phentolamine, an alpha(2)-AR antagonist. In addition, the variation in dialysate glycerol concentrations during exercise (50% peak oxygen consumption at 40 min) in a probe perfused with Ringer's solution was compared with that obtained in a probe perfused with Ringer's solution plus phentolamine. Training did not promote changes in the expression of key genes of the lipolytic pathway. The epinephrine-induced rise in the dialysate glycerol concentration was identical before and after training and was similarly potentiated by phentolamine.
Czech name
Vliv vytrvalostního tréninku na adrenergní kontrou lipolysy vtukové tkáni u obézních žen
Czech description
Byl sledován vliv 12ti týdenního vytrvalostního tréninku na geny řídící lipolýsu vpodkožní tukové tkáni (biopsie) a na úlohu adrenergní regulace (alfa(2), beta-adrenergní receptory) vtukové tkáni (metodou mikrodialýzy). Po tréninku nedošlo ke změně vexpresi genů kontrolujících lipolýzu. Trénink vedl ke snížení antilipolytického působení katecholaminů zprostředkovaného alfa(2) ARs během cvičení, pravděpodobně redukcí nárůstu katecholaminů vyvolaného cvičením.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NB6836" target="_blank" >NB6836: Dynamic resistance training in the treatment of metabolic syndrom</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Clinical Endocrinology and Metabolism
ISSN
0021-972X
e-ISSN
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Volume of the periodical
89
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
1325-1331
UT code for WoS article
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EID of the result in the Scopus database
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