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A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F06%3A00000947" target="_blank" >RIV/00216208:11120/06:00000947 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis

  • Original language description

    A double-blind, randomized study was conducted to determine whether lipid-associated amphotericin B plus Mycograb (NeuTec)is superior to amphotericin B plus placebo in patients with culture-confirmed invasive candidiasis. Mycograbrab was well tolerated.Mycograb plus lipid-associated amphotericin B produced significant clinical and culture-confirmed improvement in outcome for patients with invasive candidiasis

  • Czech name

    Randomizovaná, zaslepená, multicentrická studie se samostatně podaným lipidovým komplexem amfotericinu nebo v kombinaci s protilátkou inhibující HS 90 u pacientů s invazivní candidiazou

  • Czech description

    Dvojitě zaslepená randomizovaná multicentrická studie zaměřená na srovnání efektu lipidového komplexu Amfotericinu B a jeho kombinace s Mycograbem, protilátkou proti HS proteinu 90 u pacientů s invazivní kandidiazou. Mycograb byl dobře tolerován. Bylo prokázáno statisticky významné snížení mortality i hodnocených mikrobiologických parametrů

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Infectious Diseases

  • ISSN

    1058-4838

  • e-ISSN

  • Volume of the periodical

    42

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000237247400009

  • EID of the result in the Scopus database