Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F06%3A00001236" target="_blank" >RIV/00216208:11120/06:00001236 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases : the evolution from myeloablative to lymphoablative transplant regimens

Original language description

Hematologists/oncologists initiated the use of autologous hematopoietic stem cell transplantation. (HSCT) as a treatment for severe autoimmune diseases beginning in the early 1990s. According to multicenter reports, this therapy has been plagued by a high rate of transplant-related mortality. However, transplantrelated mortality from different individual centers varies widely. We will review and discuss how the differences in philosophy, rationale, and design of these protocols affect treatment-relatedmortality, and we will compare how these differences have influenced ongoing or soonto-be-opened randomized controlled trials of autologous HSCT for patients with autoimmune diseases. In particular, we will emphasize the distinction between myeloablativeand lymphoablative trials

Czech name

Randomizovaná kontrolovaná studie autologní transplantace hematopoetických kmenových buněk pro autoimunitní onemocnění : evoluce od myeloablativních k lymfoablativním transplantačním režimům

Czech description

Práce popisuje randomizovanou kontrolovano studii autologních transplantací hematopoetických kmenových buněk pro autoimunitní onemocnění

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Arthritis and Rheumatism

ISSN

0004-3591

e-ISSN

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Volume of the periodical

54

Issue of the periodical within the volume

12

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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