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Adiponectin as a potential marker of prostate cancer progression: studies in organ-confined and locally advanced prostate cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F08%3A00000801" target="_blank" >RIV/00216208:11120/08:00000801 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/08:1479 RIV/00064165:_____/08:1479

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Adiponectin as a potential marker of prostate cancer progression: studies in organ-confined and locally advanced prostate cancer

  • Original language description

    levels did not differ between prostate benign hyperplasia and cancer clinical stage T2, but was significantly higher in pT3 relative to pT2 group (14.51?4.92 vs. 21.41?8.12, P = 0.003). Tissue immunohistochemistry showed enhanced staining in neoplastic prostate glands and intraepithelial neoplasia relative to benign prostatic hyperplasia without distinction between disease grade and stage. Serum adiponectin levels are higher in locally advanced relative to organ-confined prostate cancer and may thus serve as an auxiliary marker providing further improvement for discrimination between pT2 and pT3 stages.

  • Czech name

    Adiponectin jako možný marker progrese u karcinomu prostaty: studie u na orgán-omezených a lokálně pokročilých karcinomů prostaty

  • Czech description

    Byly měřeny sérové hladiny adiponectinu u pacientů s benigní hyperplazií prostaty (n=25) a karcinomů stádia pT2 (n=17) a pT3 (n=26). Sérové hladiny se nelišily mezi benigní hyperplázií a karcinomem prostaty, ale byly významně vyšší u stádia T3 při srovnání se stádiem T2 (14.51+/-4.92 vs. 21.41+/-8.12, P = 0.003). Imunohistochemie prokázala zvýšenou pozitivitu v nádorové tkáni ve srovnání nenádorovými žlázkami, ale závislost na stagingu a gradu onemocnění nebyla pozorována.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Research

  • ISSN

    0862-8408

  • e-ISSN

  • Volume of the periodical

    5

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

    000257270900017

  • EID of the result in the Scopus database