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Benefits and Risks of clopidogrel use in Patients with Coronary Artery Disease: Evidence from Randomized Studies and Registries

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F08%3A00000897" target="_blank" >RIV/00216208:11120/08:00000897 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/08:#0000354

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Benefits and Risks of clopidogrel use in Patients with Coronary Artery Disease: Evidence from Randomized Studies and Registries

  • Original language description

    Background: Aggressive antiplatelet treatment is currently an established practice in patients with coronary artery disease. Objective: This article discusses the evidence from clinical trials and registries concerning the benefits and risks of clopidogrel in relation to the dose and timing of treatment and its use in particular patient populations (stratified by risk factors for major adverse cardiovascular events). Methods: Human clinical trials, registries, and in vitro human platelet studies were identified through searches of MEDLINE, Scopus, Google Scholar, and ClinicalTrials.gov (January 1980-July 2008) using the terms clopidogrel in coronary artery disease, clopidogrel loading dose, clopidogrel pretreatment, and antiplatelet therapy for coronary artery disease. For inclusion in the review, publications had to compare clopidogrel administered at different doses and times across the spectrum of patients with coronary artery disease; present outcome data on mortality, reinfarction

  • Czech name

    Přínos a rizika léčby clopidogrelem u pacientů s koronární nemocí: důkazy z randomizovaných studií a z registrů

  • Czech description

    Článek podává přehled a komentuje důkazy klinických studií a registrů týkající se léčba clopidogrelem u pacientů s koronárná nemocí

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Therapeutics

  • ISSN

    0149-2918

  • e-ISSN

  • Volume of the periodical

    8

  • Issue of the periodical within the volume

    Sp. Iss. 2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

  • UT code for WoS article

    000262062900002

  • EID of the result in the Scopus database