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Examination of Specific DNA by PCR in Patients With Different Forms of Lyme Borreliosis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F08%3A00001164" target="_blank" >RIV/00216208:11120/08:00001164 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/08:4084

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Examination of Specific DNA by PCR in Patients With Different Forms of Lyme Borreliosis

  • Original language description

    Background Borrelial specific DNA was examined in a group of 62 patients with different forms of Lyme borreliosis (LB) (32 patients suffered from neuroborreliosis, 19 manifested erythema migrans, and 11 joint involvement). Methods Nested-PCR system withfive newly derived primers was used in parallel. The study was organized prospectively, the presence of DNA was tested for plasma, CSF, joint fluid and urine before treatment, and plasma, joint fluid and urine were examined after treatment. Results Before therapy, 36 patients (58.1%) were DNA positive on the whole; 21 positive patients (65.6%) were found in the group of neuroborreliosis, 8 (42.1%) showed signs of skin involvement, and 7 (63.6%) were positive in arthritis. After treatment, 11 patients (36.7%) were positive in neuroborreliosis, 3 (17.6%) in skin form, and 6 (54.5%) in joint form of LB. Among 97 positive amplifications the most frequent target was found in primer corresponding with 16S rDNA (50 samples, 51.5%). Lower but v

  • Czech name

    Vyšetření specifické DNA pomocí PCR u pacientů s různými formami lymeské borreliózy

  • Czech description

    Byla zkoumána specifická DNA borrelií ve skupině 62 pacientů s různými formami lymeské borreliózy (32 pacientů s neuroboreliózou, 19 s manifestující erythema migrans a 11 s kloubními potížemi

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Dermatology

  • ISSN

    0011-9059

  • e-ISSN

  • Volume of the periodical

    47

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

  • UT code for WoS article

    000259525000005

  • EID of the result in the Scopus database