Leptin and adiponectin: from energy and metabolic dysbalance to inflammation and autoimmunity

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F09%3A00001948" target="_blank" >RIV/00216208:11120/09:00001948 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Leptin and adiponectin: from energy and metabolic dysbalance to inflammation and autoimmunity

Original language description

There is a growing evidence that both overnutrition and undernutrition negatively interfere with immune system. The overnutrition has been found to increase susceptibility to the development of inflammatory or autoimmune diseases. On the other hand, starvation or malnutrition has been more associated with increased susceptibility to infections. In the regulation of immune and inflammatory processes, white adipose tissue plays acritical role as an endocrine organ which produces number of active peptides,called adipokines. The adipokines, leptin and adiponectin represent acritical link among nutritional status, metabolism and immunity. Leptin is primarily known as asatiety factor regulating body weight by suppression of appetite and stimulation of energy expenditure, and its serum levels and gene expression in adipocytes strongly correlate with proportion of body fat stores. On the other hand, leptin is apro-inflammatory adipokine inducing Thelper 1cells and may contribute to the develo

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Endocrine Regulations

ISSN

1210-0668

e-ISSN

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Volume of the periodical

43

Issue of the periodical within the volume

4

Country of publishing house

SK - SLOVAKIA

Number of pages

12

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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